The Simons Center for Quantitative Biology is launching a new post-doctoral training program designed to support quantitative scientists who want to transition into biology, with a particular focus on machine learning and data science. The Simons Center is the home for mathematical, computational, and theoretical research in biology at Cold Spring Harbor Laboratory. The Center includes over a dozen faculty members developing innovative methods to tackle fundamental problems in areas, such as neuroscience, genomics, plant biology, and cancer, with extensive collaborations with experimentalists in a world-class research and education institution.