ID: uc001txo.3
GENE: GCN1L1(3)
chr12:120569088-120569337-


(2)
AGO1.ip 		(1)
AGO1.ip OTHER.mut 		(2)
AGO2.ip 		(2)
B-CELL 		(5)
BREAST 		(16)
CELL-LINE 		(1)
CERVIX 		(1)
FIBROBLAST 		(1)
HEART 		(4)
HELA 		(1)
KIDNEY 		(1)
LIVER 		(1)
OTHER 		(10)
SKIN 		(1)
XRN.ip

Sense strand
GCTTTCCTTACTTTCCTTAATGTGCCACTTTGGGGAGCTTCTGCCAAGATAGCAGGGAGGTCCATGTGAATGTGGCCTGGAGTTTTCCTTGTGCTCTGGGTCAGCACACTGGTCTCCAGCGGGGTGGGCCCATGGGCCTCATGGGTGCTGGGGACATGCTGTAAAATACCGGTTGATCCCAGTCGTGTCCTTCCACCCAGCGGACGTGTCCGGCATTGACTGGATGGTTCGGCACGGGCGGAGCCTGGCA
.............................................................................................................................................((((((..((((((((((((...(((....))).....))).))))))))).))))))...................................................
.......................................................................................................................................136.............................................................200................................................
SizePerfect hitTotal NormPerfect NormSRR207114(GSM721076)
IP against AGO 1 & 2, RRP40 knockdown. (ago1/2 RRP40 cell line)		SRR387910(GSM843862)
antibody for ip: Ago2. (ago2 cell line)		SRR189782SRR326279(GSM769509)
cytoplasmic fraction was isolated using PARIS. (cell line)		SRR207113(GSM721075)
IP against AGO 1 & 2. (ago1/2 cell line)		SRR207115(GSM721077)
XRN1&2 knockdown. (XRN1/XRN2 cell line)		RoviraIPAgo2(Rovira)
total RNA. (ago2 breast)		DRR001488(DRX001042)
Hela short nuclear cell fraction, LNA(+). (hela)		SRR189779(GSM714639)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		GSM1105748AGO1(GSM1105748)
small RNA sequencing data. (ago1 hela)		SRR033722(GSM497067)
KMS12 cell line (KMS12). (B cell)		SRR189780(GSM714640)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR330896(SRX091734)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR191614(GSM715724)
92genomic small RNA (size selected RNA from t. (breast)		SRR033717(GSM497062)
Mentle Cell Lymphoma (MCL112). (B cell)		GSM532883(GSM532883)
G871N. (cervix)		SRR037944(GSM510482)
293DcrTN_cand5. (cell line)		SRR039190(GSM494809)
PBMCs were isolated by ficoll gradient from t. (blood)		SRR553575(SRX182781)
source: Kidney. (Kidney)		SRR330889(SRX091727)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR039192(GSM494811)
K562 cell line is derived from a CML patient . (cell line)		SRR037936(GSM510474)
293cand1. (cell line)		SRR326280(GSM769510)
total cell content of unperturbed cells was s. (cell line)		SRR330914(SRX091752)
tissue: normal skindisease state: normal. (skin)		SRR039625(GSM531988)
HBV(-) HCV(-) HCC Tissue Sample. (liver)		SRR191591(GSM715701)
53genomic small RNA (size selected RNA from t. (breast)		SRR038857(GSM458540)
D20. (cell line)		SRR343332(GSM796035)
KSHV (HHV8), EBV (HHV-4). (cell line)		SRR037876(GSM522374)
fibroblasts_cell_culture. (fibroblast)		GSM359176(GSM359176)
hela_chip_smrna_pure. (hela)		DRR000558(DRX000316)
THP-1 whole cell RNA, after 3 day treatment w. (cell line)		SRR330867(SRX091705)
tissue: skin psoriatic involveddisease state:. (skin)		TAX577745(Rovira)
total RNA. (breast)		SRR189787DRR000555(DRX000313)
THP-1 whole cell RNA, no treatment. (cell line)		SRR326282(GSM769512)
Dicer mRNA was knocked down using siDicer, to. (cell line)		DRR001489(DRX001043)
Hela short nuclear cell fraction, control. (hela)		SRR330901(SRX091739)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR191421(GSM715531)
122genomic small RNA (size selected RNA from . (breast)		SRR444054(SRX128902)
Sample 14cDNABarcode: AF-PP-342: ACG CTC TTC . (skin)		SRR330911(SRX091749)
tissue: normal skindisease state: normal. (skin)		SRR444049(SRX128897)
Sample 9cDNABarcode: AF-PP-334: ACG CTC TTC C. (skin)		SRR330883(SRX091721)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR444046(SRX128894)
Sample 7cDNABarcode: AF-PP-342: ACG CTC TTC C. (skin)		SRR342896(SRX096792)
small RNA seq of Right atrial tissue. (heart)
............................................................................................................................................ATGGGTGCTGGGGACATGCTGT........................................................................................22115.0015.006.00--2.00-2.00-2.00-----1.00--------1.00------------1.00---------
...........................................................................................................................................CATGGGTGCTGGGGACATGCTGT........................................................................................2319.009.00-2.00--4.00-----------1.001.00----------------1.00----------
............................................................................................................................................ATGGGTGCTGGGGACATGCTG.........................................................................................2115.005.00-5.00-------------------------------------------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGTA.......................................................................................2314.004.003.00------------------------1.00-------------------
............................................................................................................................................................................................................................TGGATGGTTCGGCACGGGCGGAA.......2313.001.00-3.00-------------------------------------------
.............................................................................................................................................TGGGTGCTGGGGACATGCTGT........................................................................................2113.003.00---1.00---1.00----------------------1.00--------------
..................................................................................................................................................................................CCAGTCGTGTCCTTCCACCCAGA.................................................2312.002.00--1.00------1.00-----------------------------------
.....................................................................................................................................................................................................................................CGGCACGGGCGGAGCGC....172.000.00---1.00-----------1.00-----------------------------
.....................................................................................................................................................................................................................CATTGACTGGATGGTTCGGCACGGGCGGAG.......3012.002.00------2.00--------------------------------------
..................................................................................................................................................................................CCAGTCGTGTCCTTCCACCCAG..................................................2212.002.00--1.00---1.00--------------------------------------
...........................................................................................................................................CATGGGTGCTGGGGACATGC...........................................................................................2012.002.002.00--------------------------------------------
..........................................................................................................................................TCATGGGTGCTGGGGACATGCTG.........................................................................................2311.001.00-----1.00---------------------------------------
................................................................................................................................................................................................................................TGGTTCGGCACGGGCGGAGCCCGGC.251.000.00--------1.00------------------------------------
........................................................................................................................................................................................................................TGACTGGATGGTTCGGCACGGGCGGAGCCCGG..321.000.00-----------1.00---------------------------------
...............................................................................................................................................................................................................................ATGGTTCGGCACGGGCGG.........1811.001.00-------------------------------------1.00-------
.............................................................................................................................................TGGGTGCTGGGGACATGCTG.........................................................................................2011.001.00------------------1.00--------------------------
...................................................GCAGGGAGGTCCATGTGAATT..................................................................................................................................................................................211.000.00--1.00------------------------------------------
..................................................................................................................TCCAGCGGGGTGGGCTT.......................................................................................................................171.000.00-----------1.00---------------------------------
.............................................AAGATAGCAGGGAGGGGTC..........................................................................................................................................................................................191.000.00--------1.00------------------------------------
............................................................................................................................................ATGGGTGCTGGGGACATGAAA.........................................................................................211.000.00---------1.00-----------------------------------
...............................................................................................................................................................................................................................ATGGTTCGGCACGGGCGGAGCCTGGCAAC291.000.00--------1.00------------------------------------
.......................................................................................................................................................................................................................TTGACTGGATGGTTCGGCACGGGC...........2411.001.00------------1.00--------------------------------
.....................................................................................................................................................................................GTCGTGTCCTTCCACCCAG..................................................1911.001.00----1.00----------------------------------------
.............................................................................................................................................................................................................................GGATGGTTCGGCACGGGCGG.........2011.001.00------------1.00--------------------------------
...................................................................................................................................................................................CAGTCGTGTCCTTCCACCCAG..................................................2111.001.00------------------------1.00--------------------
.......................................................................................................................................................................................................................TTGACTGGATGGTTCGGCACGGGCGGAGCC.....3011.001.00-------------------------------1.00-------------
............................................................................................................................................................................................................................TGGATGGTTCGGCACGGGCGG.........2111.001.00----------1.00----------------------------------
............................................................................................................................TGGGCCCATGGGCCTCATGGGTGCTG....................................................................................................2611.001.00-----------------------------1.00---------------
...................................................GCAGGGAGGTCCATGTACAG...................................................................................................................................................................................201.000.00--1.00------------------------------------------
...........................................................................................................................................CATGGGTGCTGGGGACATG............................................................................................1911.001.00--1.00------------------------------------------
....................................................................................................................................................................................AGTCGTGTCCTTCCACCCAGCGGACGTGT.........................................2911.001.00-------------------1.00-------------------------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGTTGT.....................................................................................2511.0015.00-----1.00---------------------------------------
.............................................................................................................................................TGGGTGCTGGGGACATGCT..........................................................................................1911.001.00--------------------------------------1.00------
............................................................................................................................................ATGGGTGCTGGGGACATGCTAT........................................................................................221.000.00--------------------1.00------------------------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGTAT......................................................................................2411.004.00---------------------1.00-----------------------
...........................................................................................................................................................................................................ACGTGTCCGGCATTGACTG............................1911.001.00----------1.00----------------------------------
............................................................................................................................................................................................................................TGGATGGTTCGGCACGGGCGGAT.......2311.001.00--------------1.00------------------------------
..................................................................................................................................................................................................................CGGCATTGACTGGATGGTTCGGCACGGG............2811.001.00------------------------------------1.00--------
...................................................................................................................................................................................CAGTCGTGTCCTTCCACCCAGA.................................................2211.001.00--------------------------1.00------------------
.............................................................................................................................................TGGGTGCTGGGGACATGCTGTA.......................................................................................2211.001.00------1.00--------------------------------------
.....................................................................................................................................................................................................................CATTGACTGGATGGTTCGGC.................2011.001.00-----------------------1.00---------------------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGGA.......................................................................................2311.005.00---1.00-----------------------------------------
...................................................GCAGGGAGGTCCATGTGAAGT..................................................................................................................................................................................211.000.00--1.00------------------------------------------
............................................................................................................................................................................................................................TGGATGGTTCGGCACGGGCGGA........2211.001.00-1.00-------------------------------------------
...........................................................................................................................................CATGGGTGCTGGGGACATGCT..........................................................................................2111.001.00---------1.00-----------------------------------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGCA.......................................................................................2311.005.00---------------------------------1.00-----------
............................................................................................................................................ATGGGTGCTGGGGACATGCTGTAA......................................................................................2411.001.00---------------------------1.00-----------------
.........................................................................................................................................................................................................GGACGTGTCCGGCAT..................................1520.500.50----------------------------------------0.50----
.......................................................................................................................................................................................................................................GCACGGGCGGAGCC.....1450.200.20---0.20-----------------------------------------
.....................................................................................................................................................................................................................................CGGCACGGGCGGAG.......1450.200.20------------------------------------------0.20--
.........................................................................................................................................................................................................................................ACGGGCGGAGCCTG...1450.200.20--------------------------------------------0.20

Antisense strand
GCTTTCCTTACTTTCCTTAATGTGCCACTTTGGGGAGCTTCTGCCAAGATAGCAGGGAGGTCCATGTGAATGTGGCCTGGAGTTTTCCTTGTGCTCTGGGTCAGCACACTGGTCTCCAGCGGGGTGGGCCCATGGGCCTCATGGGTGCTGGGGACATGCTGTAAAATACCGGTTGATCCCAGTCGTGTCCTTCCACCCAGCGGACGTGTCCGGCATTGACTGGATGGTTCGGCACGGGCGGAGCCTGGCA
.............................................................................................................................................((((((..((((((((((((...(((....))).....))).))))))))).))))))...................................................
.......................................................................................................................................136.............................................................200................................................
SizePerfect hitTotal NormPerfect NormSRR207114(GSM721076)
IP against AGO 1 & 2, RRP40 knockdown. (ago1/2 RRP40 cell line)		SRR387910(GSM843862)
antibody for ip: Ago2. (ago2 cell line)		SRR189782SRR326279(GSM769509)
cytoplasmic fraction was isolated using PARIS. (cell line)		SRR207113(GSM721075)
IP against AGO 1 & 2. (ago1/2 cell line)		SRR207115(GSM721077)
XRN1&2 knockdown. (XRN1/XRN2 cell line)		RoviraIPAgo2(Rovira)
total RNA. (ago2 breast)		DRR001488(DRX001042)
Hela short nuclear cell fraction, LNA(+). (hela)		SRR189779(GSM714639)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		GSM1105748AGO1(GSM1105748)
small RNA sequencing data. (ago1 hela)		SRR033722(GSM497067)
KMS12 cell line (KMS12). (B cell)		SRR189780(GSM714640)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR330896(SRX091734)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR191614(GSM715724)
92genomic small RNA (size selected RNA from t. (breast)		SRR033717(GSM497062)
Mentle Cell Lymphoma (MCL112). (B cell)		GSM532883(GSM532883)
G871N. (cervix)		SRR037944(GSM510482)
293DcrTN_cand5. (cell line)		SRR039190(GSM494809)
PBMCs were isolated by ficoll gradient from t. (blood)		SRR553575(SRX182781)
source: Kidney. (Kidney)		SRR330889(SRX091727)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR039192(GSM494811)
K562 cell line is derived from a CML patient . (cell line)		SRR037936(GSM510474)
293cand1. (cell line)		SRR326280(GSM769510)
total cell content of unperturbed cells was s. (cell line)		SRR330914(SRX091752)
tissue: normal skindisease state: normal. (skin)		SRR039625(GSM531988)
HBV(-) HCV(-) HCC Tissue Sample. (liver)		SRR191591(GSM715701)
53genomic small RNA (size selected RNA from t. (breast)		SRR038857(GSM458540)
D20. (cell line)		SRR343332(GSM796035)
KSHV (HHV8), EBV (HHV-4). (cell line)		SRR037876(GSM522374)
fibroblasts_cell_culture. (fibroblast)		GSM359176(GSM359176)
hela_chip_smrna_pure. (hela)		DRR000558(DRX000316)
THP-1 whole cell RNA, after 3 day treatment w. (cell line)		SRR330867(SRX091705)
tissue: skin psoriatic involveddisease state:. (skin)		TAX577745(Rovira)
total RNA. (breast)		SRR189787DRR000555(DRX000313)
THP-1 whole cell RNA, no treatment. (cell line)		SRR326282(GSM769512)
Dicer mRNA was knocked down using siDicer, to. (cell line)		DRR001489(DRX001043)
Hela short nuclear cell fraction, control. (hela)		SRR330901(SRX091739)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR191421(GSM715531)
122genomic small RNA (size selected RNA from . (breast)		SRR444054(SRX128902)
Sample 14cDNABarcode: AF-PP-342: ACG CTC TTC . (skin)		SRR330911(SRX091749)
tissue: normal skindisease state: normal. (skin)		SRR444049(SRX128897)
Sample 9cDNABarcode: AF-PP-334: ACG CTC TTC C. (skin)		SRR330883(SRX091721)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR444046(SRX128894)
Sample 7cDNABarcode: AF-PP-342: ACG CTC TTC C. (skin)		SRR342896(SRX096792)
small RNA seq of Right atrial tissue. (heart)
.....................................................................................................................................................................................GTCGTGTCCTTCCACGATC.................................................. 191.000.00----------------------------1.00----------------
...........................................CCAAGATAGCAGGGATTTT............................................................................................................................................................................................ 191.000.00--------------------------------1.00------------
......................................................................................................................GCGGGGTGGGCCCAT..................................................................................................................... 1520.500.50---------------------------------------0.50-----
..........................................................................................................................................................................................................................ACTGGATGGTTCG................... 1350.400.40-----------------------------------------0.20-0.20-