ID: uc008irh.13
GENE: Grin1(6)
chr2:25160683-25160854-


(18)
AGO2.ip 		(42)
BRAIN 		(2)
CELL-LINE 		(3)
DCR.mut 		(2)
DGCR8.mut 		(3)
EMBRYO 		(4)
ESC 		(1)
FIBROBLAST 		(1)
LIVER 		(1)
LUNG 		(6)
OTHER 		(3)
PIWI.ip 		(11)
TESTES 		(1)
TOTAL-RNA

Sense strand
CGTCGGGGAGCGCGAGATCTCTGGGAATGCCCTGCGCTACGCTCCTGACGGTGAGTGCTGGGCTGTGGGGTCGCCTGGGACTGTAGGCCAGTCCAGTCTCTAAGCTCCAGGGTCCCGCGCAGGCATCATCGGACTTCAGCTAATCAACGGCAAGAACGAGTCGGCCCACATC
...........................................................(((((.((((((.....(((((((..((....)))))))))...)))))).))))).........................................................
..........................................................59.............................................................122................................................
SizePerfect hitTotal NormPerfect NormSRR306542(GSM750585)
19-24nt. (ago2 brain)		SRR306535(GSM750578)
19-24nt. (ago2 brain)		SRR306541(GSM750584)
19-24nt. (ago2 brain)		SRR038742(GSM527277)
small RNA-Seq. (dgcr8 brain)		SRR306536(GSM750579)
19-24nt. (ago2 brain)		SRR306532(GSM750575)
19-24nt. (ago2 brain)		SRR306534(GSM750577)
19-24nt. (ago2 brain)		SRR306533(GSM750576)
19-24nt. (ago2 brain)		SRR553583(SRX182789)
source: Cerebellum. (Cerebellum)		SRR038744(GSM527279)
small RNA-Seq. (brain)		SRR306531(GSM750574)
19-24nt. (ago2 brain)		SRR306530(GSM750573)
19-24nt. (ago2 brain)		SRR306540(GSM750583)
19-24nt. (ago2 brain)		SRR306529(GSM750572)
19-24nt. (ago2 brain)		SRR306537(GSM750580)
19-24nt. (ago2 brain)		SRR039610(GSM527274)
small RNA-Seq. (brain)		SRR306544(GSM750587)
19-24nt. (ago2 brain)		mjTestesWT4()
Testes Data. (testes)		SRR346417(SRX098258)
Global profiling of miRNA and the hairpin pre. (Brain)		SRR306527(GSM750570)
19-24nt. (ago2 brain)		SRR038740(GSM527275)
small RNA-Seq. (dicer brain)		GSM314557(GSM314557)
ESC dgcr8 (Illumina). (ESC)		GSM510444(GSM510444)
brain_rep5. (brain)		SRR346423(SRX098265)
Global profiling of miRNA and the hairpin pre. (Brain)		SRR037906(GSM510442)
brain_rep3. (brain)		SRR345198(SRX097259)
source: size fractionated RNA from mouse hipp. (brain)		SRR306543(GSM750586)
19-24nt. (ago2 brain)		SRR206939(GSM723280)
other. (brain)		SRR206942(GSM723283)
other. (brain)		SRR206941(GSM723282)
other. (brain)		SRR553582(SRX182788)
source: Brain. (Brain)		SRR345196(SRX097257)
source: size fractionated RNA from mouse hipp. (brain)		SRR306526(GSM750569)
19-24nt. (ago2 brain)		SRR279906(GSM689056)
cell type: mouse embryonic stem cellcell line. (ESC)		SRR206940(GSM723281)
other. (brain)		SRR038745(GSM527280)
small RNA-Seq. (dgcr8 brain)		SRR391852(GSM852147)
gender: femalegenotype/variation: ADAR2-/-tis. (embryo)		SRR546155(SRX180174)
Global profiling of miRNA and the hairpin pre. (ago2 Neuroblastoma)		SRR345200(SRX097261)
source: size fractionated RNA from mouse hipp. (brain)		SRR038741(GSM527276)
small RNA-Seq. (brain)		SRR037905(GSM510441)
brain_rep2. (brain)		SRR391845(GSM852140)
gender: femalegenotype/variation: wild typeti. (embryo)		SRR306539(GSM750582)
19-24nt. (ago2 brain)		SRR279903(GSM689053)
cell type: mouse embryonic stem cellcell line. (ESC)		SRR037901(GSM510437)
testes_rep2. (testes)		SRR037903(GSM510439)
testes_rep4. (testes)		SRR040488(GSM533911)
E18.5 wild type LIVER small RNA. (liver)		SRR073955(GSM629281)
total RNA. (blood)		mjTestesWT2()
Testes Data. (testes)		GSM509280(GSM509280)
small RNA cloning by length. (testes)		SRR037904(GSM510440)
brain_rep1. (brain)		SRR391848(GSM852143)
gender: femalegenotype/variation: wild typeti. (embryo)		SRR042477(GSM539869)
mouse brain tissue [09-002]. (brain)		SRR402766(SRX117949)
source: ES PGK female cells. (ESC)		SRR346425(SRX098267)
Global profiling of miRNA and the hairpin pre. (Neuroblastoma)		SRR345202(SRX097263)
source: size fractionated RNA from mouse hipp. (brain)		SRR038743(GSM527278)
small RNA-Seq. (dicer brain)		SRR034118(GSM466728)
Mili IP_Tdrd9+/- replicate1. (mili testes)		SRR037912(GSM510449)
newborn_rep5. (total RNA)		SRR034120(GSM466730)
Mili IP_Tdrd9-/- replicate1. (mili testes)		SRR069809(GSM610965)
small RNA sequencing; sample 1. (testes)		SRR023850(GSM307159)
ZHBT-c40hsmallrna_rep1. (cell line)		SRR069811(GSM610967)
small RNA sequencing; sample 3. (testes)		SRR039186(GSM485326)
shLuc.1309;ROSA-rtTA (+dox). (fibroblast)		SRR346424(SRX098266)
Global profiling of miRNA and the hairpin pre. (Neuroblastoma)		SRR345201(SRX097262)
source: size fractionated RNA from mouse hipp. (brain)		SRR034119(GSM466729)
Mili IP_Tdrd9+/- replicate2. (mili testes)		SRR060845(GSM561991)
total RNA. (brain)		SRR346421(SRX098263)
Global profiling of miRNA and the hairpin pre. (mixture)		SRR394084(GSM855970)
"background strain: C57BL6/SV129cell type: KR. (dicer cell line)		SRR346419(SRX098260)
Global profiling of miRNA and the hairpin pre. (Lung)		SRR037902(GSM510438)
testes_rep3. (testes)
....................................................................................................TAAGCTCCAGGGTCCCGCGCAG..................................................221104.00104.0016.008.008.003.004.003.008.006.003.003.006.004.003.004.001.001.002.00-2.004.00-1.00--3.00-2.002.00-1.00--1.00-1.00--1.00-2.00--1.00-----------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAGT.................................................23177.00104.008.007.009.001.003.008.005.004.00--3.001.003.002.004.00-2.00-1.003.00-2.001.00-1.00-1.001.00----2.00-2.00-----2.00------------1.00------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGC....................................................20133.0033.002.002.004.001.003.001.003.002.001.001.002.00-2.001.001.00-1.00-----1.00-1.00----2.001.00----1.00------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCA...................................................21123.0023.001.002.001.001.004.001.00-1.001.00--2.00--1.00-2.00----1.002.001.00------------------1.00-------1.00---------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAGA.................................................2318.00104.00--1.001.00--------1.00---1.00-2.00--------1.00--1.00-----------------------------------------
...........................................................................................................................CATCATCGGACTTCAGCT...............................1818.008.00---------3.00-----2.00----3.00---------------------------------------------------
...............................................................TGTGGGGTCGCCTGGGACTGTAG......................................................................................2317.007.00--------4.00---------1.00------------------1.00----------------1.00-----------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAT..................................................2217.0023.00--1.001.001.00---1.00---1.00-1.00-------1.00-------------------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCTT..................................................2216.0033.001.00---------1.003.00--1.00---------------------------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCT...................................................2116.0033.00-1.00---2.00-1.00---1.00----------------1.00-------------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAGC.................................................2315.00104.00-1.00-----------2.00----1.00------------------------------------------1.00----------
..........................................................................................................................GCATCATCGGACTTCAGCT...............................1915.005.00---1.00-----1.00----------1.00----1.00---------1.00------------------------------------
.............................................................................................................................TCATCGGACTTCAGCTAATCAACGG......................2513.003.00---------------2.00----1.00---------------------------------------------------
...............................................................TGTGGGGTCGCCTGGGACTGTAGT.....................................................................................2413.007.00------------------------------2.00---------------------1.00-------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAGTT................................................2412.00104.00---------------------2.00--------------------------------------------------
..........................................................................................................................GCATCATCGGACTTCAGC................................1812.002.00--------------------1.00-----------------------------------1.00---------------
...............................................................TGTGGGGTCGCCTGGGACTGTAGGTT...................................................................................2612.002.00-----------------------1.00-------------1.00----------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCAA..................................................2212.0023.00-----1.00-----------------1.00------------------------------------------------
....................................................GAGTGCTGGGCTGTGGGGT.....................................................................................................1912.002.00----------------------------------------------2.00-------------------------
...............................................................TGTGGGGTCGCCTGGGACTGT........................................................................................2112.002.00-------1.00--------------------------------------------------------1.00-------
...............................................................TGTGGGGTCGCCTGGGACTGTAGG.....................................................................................2412.002.00--------1.001.00--------------------------------------------------------------
.........................................................................................................................GGCATCATCGGACTTCAGCT...............................2012.002.00---------------1.00-------------------1.00------------------------------------
.................................GCGCTACGCTCCTGACG..........................................................................................................................1712.002.00---------------------------------2.00--------------------------------------
.................................................................................................................................CGGACTTCAGCTAATCAACGGCAAGAACG..............2912.002.00---2.00--------------------------------------------------------------------
..................................................................................................................................................ACGGCAAGAACGAGTCG.........1712.002.00-2.00----------------------------------------------------------------------
............................................................................................................................ATCATCGGACTTCAGCT...............................1712.002.00---------1.00-----1.00--------------------------------------------------------
..........................................................................................................................GCATCATCGGACTTCAGCTAATC...........................2311.001.00---------1.00--------------------------------------------------------------
...............................................................TGTGGGGTCGCCTGGGACTGTTAT.....................................................................................2411.002.00--------1.00---------------------------------------------------------------
..................................................GTGAGTGCTGGGCTGTGA........................................................................................................181.000.00-----------------------1.00------------------------------------------------
...........................................................................................................................CATCATCGGACTTCAGC................................1711.001.00---------------1.00--------------------------------------------------------
...........................................................................................................................CATCATCGGACTTCAGCTA..............................1911.001.00---1.00--------------------------------------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCTTT.................................................2311.0033.00-1.00----------------------------------------------------------------------
...........................................................................................................................CATCATCGGACTTCAGCTAATCAACGG......................2711.001.00---1.00--------------------------------------------------------------------
....................................................................................................................................................GGCAAGAACGAGTCGAGC......181.000.00-----------------------------------------------1.00------------------------
........................................................................................................CTCCAGGGTCCCGCGCAG..................................................1811.001.00-------------1.00----------------------------------------------------------
............................................................................................................................ATCATCGGACTTCAGCTAATCAACGGCAA...................2911.001.00---------------------------------------------------------1.00--------------
..................................................GTGAGTGCTGGGCTGTGAA.......................................................................................................191.000.00--------1.00---------------------------------------------------------------
..................................................GTGAGTGCTGGGCTGTGGGGTCGCCTGGGACTGTAGGCCAGTCCAGTCTCTAAGCTCCAGGGTCCCGCGCAGT.................................................731.000.00--------------------------------------------------------------------1.00---
........................................................................................................................................................AGAACGAGTCGGCCCACA..1811.001.00---1.00--------------------------------------------------------------------
..........................................................................................................................GCATCATCGGACTTCGGGC...............................191.000.00--------------------------------------1.00---------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCTA..................................................2211.0033.00-------------1.00----------------------------------------------------------
.................TCTCTGGGAATGCCCTGCGCT......................................................................................................................................2111.001.00-------------------------------------------1.00----------------------------
.........................................................................................................................................................GAACGAGTCGGCCCACATC1911.001.00-------------------------------------------------------1.00----------------
.............................................................................................................................TCATCGGACTTCAGCTGTGC...........................201.000.00---1.00--------------------------------------------------------------------
...................................................................................TAGGCCAGTCCAGTCTCTAAGCTCT................................................................251.000.00---1.00--------------------------------------------------------------------
.........................AATGCCCTGCGCTACGC..................................................................................................................................1711.001.00---------------------------------1.00--------------------------------------
.................................................................TGGGGTCGCCTGGGACTGTAGGTTT..................................................................................2511.001.00-----------------------1.00------------------------------------------------
....................................................................................................TAAGCTCCAGGGTCCCGCGCATT.................................................2311.0023.00-1.00----------------------------------------------------------------------
..........................................................................................................................GCATCATCGGACTTCTGTT...............................191.000.00-------------------------1.00----------------------------------------------
...............................................................TGTGGGGTCGCCTGGGACTGTAT......................................................................................231.000.00--------------------------1.00---------------------------------------------
............................................................GGCTGTGGGGTCGCCACC..............................................................................................181.000.00-----------------------------------------------1.00------------------------
.................................................................TGGGGTCGCCTGGGACTGTAGG.....................................................................................2211.001.00---1.00--------------------------------------------------------------------
..................................................................................................................................GGACTTCAGCTAATCAACGG......................2011.001.00----------------------------1.00-------------------------------------------
...........................................................................................................................CATCATCGGACTTCAGCTAATCAACG.......................2611.001.00---------------------------------------1.00--------------------------------
......................................................................................................................................................CAAGAACGAGTCGGCCCAC...1911.001.00----------------------------------------------------------1.00-------------
......................................ACGCTCCTGACGGTGATAGG..................................................................................................................201.000.00------------1.00-----------------------------------------------------------
..................................................................................................................................GGACTTCAGCTAATCAACGGCAAGAACG..............2811.001.00----------------------------1.00-------------------------------------------
...............................................................................................................................ATCGGACTTCAGCTAATC...........................1811.001.00---------1.00--------------------------------------------------------------
.................................................GGTGAGTGCTGGGCTAGAG........................................................................................................191.000.00-----------------------------------------------------------------1.00------
..................................................................................................................................................ACGGCAAGAACGAGTCGGC.......1911.001.00----------------------------------------------------------------------1.00-
.....................................................................................................................................................GCAAGAACGAGTCGGCCCACATC2311.001.00----------------------------1.00-------------------------------------------
..........CGCGAGATCTCTGGGAATGCC.............................................................................................................................................2111.001.00-----------------------------1.00------------------------------------------
....................................................GAGTGCTGGGCTGTGGG.......................................................................................................1720.500.50--------0.50---------------------------------------------------------------
.......................................................................CGCCTGGGACTGTAG......................................................................................1540.250.25--------0.25---------------------------------------------------------------
....................................................................................................TAAGCTCCAGGGTCC.........................................................1590.110.11-------0.11----------------------------------------------------------------

Antisense strand
CGTCGGGGAGCGCGAGATCTCTGGGAATGCCCTGCGCTACGCTCCTGACGGTGAGTGCTGGGCTGTGGGGTCGCCTGGGACTGTAGGCCAGTCCAGTCTCTAAGCTCCAGGGTCCCGCGCAGGCATCATCGGACTTCAGCTAATCAACGGCAAGAACGAGTCGGCCCACATC
...........................................................(((((.((((((.....(((((((..((....)))))))))...)))))).))))).........................................................
..........................................................59.............................................................122................................................
SizePerfect hitTotal NormPerfect NormSRR306542(GSM750585)
19-24nt. (ago2 brain)		SRR306535(GSM750578)
19-24nt. (ago2 brain)		SRR306541(GSM750584)
19-24nt. (ago2 brain)		SRR038742(GSM527277)
small RNA-Seq. (dgcr8 brain)		SRR306536(GSM750579)
19-24nt. (ago2 brain)		SRR306532(GSM750575)
19-24nt. (ago2 brain)		SRR306534(GSM750577)
19-24nt. (ago2 brain)		SRR306533(GSM750576)
19-24nt. (ago2 brain)		SRR553583(SRX182789)
source: Cerebellum. (Cerebellum)		SRR038744(GSM527279)
small RNA-Seq. (brain)		SRR306531(GSM750574)
19-24nt. (ago2 brain)		SRR306530(GSM750573)
19-24nt. (ago2 brain)		SRR306540(GSM750583)
19-24nt. (ago2 brain)		SRR306529(GSM750572)
19-24nt. (ago2 brain)		SRR306537(GSM750580)
19-24nt. (ago2 brain)		SRR039610(GSM527274)
small RNA-Seq. (brain)		SRR306544(GSM750587)
19-24nt. (ago2 brain)		mjTestesWT4()
Testes Data. (testes)		SRR346417(SRX098258)
Global profiling of miRNA and the hairpin pre. (Brain)		SRR306527(GSM750570)
19-24nt. (ago2 brain)		SRR038740(GSM527275)
small RNA-Seq. (dicer brain)		GSM314557(GSM314557)
ESC dgcr8 (Illumina). (ESC)		GSM510444(GSM510444)
brain_rep5. (brain)		SRR346423(SRX098265)
Global profiling of miRNA and the hairpin pre. (Brain)		SRR037906(GSM510442)
brain_rep3. (brain)		SRR345198(SRX097259)
source: size fractionated RNA from mouse hipp. (brain)		SRR306543(GSM750586)
19-24nt. (ago2 brain)		SRR206939(GSM723280)
other. (brain)		SRR206942(GSM723283)
other. (brain)		SRR206941(GSM723282)
other. (brain)		SRR553582(SRX182788)
source: Brain. (Brain)		SRR345196(SRX097257)
source: size fractionated RNA from mouse hipp. (brain)		SRR306526(GSM750569)
19-24nt. (ago2 brain)		SRR279906(GSM689056)
cell type: mouse embryonic stem cellcell line. (ESC)		SRR206940(GSM723281)
other. (brain)		SRR038745(GSM527280)
small RNA-Seq. (dgcr8 brain)		SRR391852(GSM852147)
gender: femalegenotype/variation: ADAR2-/-tis. (embryo)		SRR546155(SRX180174)
Global profiling of miRNA and the hairpin pre. (ago2 Neuroblastoma)		SRR345200(SRX097261)
source: size fractionated RNA from mouse hipp. (brain)		SRR038741(GSM527276)
small RNA-Seq. (brain)		SRR037905(GSM510441)
brain_rep2. (brain)		SRR391845(GSM852140)
gender: femalegenotype/variation: wild typeti. (embryo)		SRR306539(GSM750582)
19-24nt. (ago2 brain)		SRR279903(GSM689053)
cell type: mouse embryonic stem cellcell line. (ESC)		SRR037901(GSM510437)
testes_rep2. (testes)		SRR037903(GSM510439)
testes_rep4. (testes)		SRR040488(GSM533911)
E18.5 wild type LIVER small RNA. (liver)		SRR073955(GSM629281)
total RNA. (blood)		mjTestesWT2()
Testes Data. (testes)		GSM509280(GSM509280)
small RNA cloning by length. (testes)		SRR037904(GSM510440)
brain_rep1. (brain)		SRR391848(GSM852143)
gender: femalegenotype/variation: wild typeti. (embryo)		SRR042477(GSM539869)
mouse brain tissue [09-002]. (brain)		SRR402766(SRX117949)
source: ES PGK female cells. (ESC)		SRR346425(SRX098267)
Global profiling of miRNA and the hairpin pre. (Neuroblastoma)		SRR345202(SRX097263)
source: size fractionated RNA from mouse hipp. (brain)		SRR038743(GSM527278)
small RNA-Seq. (dicer brain)		SRR034118(GSM466728)
Mili IP_Tdrd9+/- replicate1. (mili testes)		SRR037912(GSM510449)
newborn_rep5. (total RNA)		SRR034120(GSM466730)
Mili IP_Tdrd9-/- replicate1. (mili testes)		SRR069809(GSM610965)
small RNA sequencing; sample 1. (testes)		SRR023850(GSM307159)
ZHBT-c40hsmallrna_rep1. (cell line)		SRR069811(GSM610967)
small RNA sequencing; sample 3. (testes)		SRR039186(GSM485326)
shLuc.1309;ROSA-rtTA (+dox). (fibroblast)		SRR346424(SRX098266)
Global profiling of miRNA and the hairpin pre. (Neuroblastoma)		SRR345201(SRX097262)
source: size fractionated RNA from mouse hipp. (brain)		SRR034119(GSM466729)
Mili IP_Tdrd9+/- replicate2. (mili testes)		SRR060845(GSM561991)
total RNA. (brain)		SRR346421(SRX098263)
Global profiling of miRNA and the hairpin pre. (mixture)		SRR394084(GSM855970)
"background strain: C57BL6/SV129cell type: KR. (dicer cell line)		SRR346419(SRX098260)
Global profiling of miRNA and the hairpin pre. (Lung)		SRR037902(GSM510438)
testes_rep3. (testes)
............................GCCCTGCGCTACGCTCCTGACGGTGA...................................................................................................................... 2617.007.00-----------------7.00------------------------------------------------------
.............GAGATCTCTGGGAATTTGT............................................................................................................................................ 195.000.00--------------------------------------------2.002.00-------------------------1.00
...................................................................................TAGGCCAGTCCAGTCTCT....................................................................... 1814.004.00-------------------------1.00-----2.00----------------------------1.00-----------
.......................................................................................................................CAGGCATCATCGGACTTCAGCTAATCA.......................... 2712.002.00-----------------------------------------------------------1.00------1.00-----
...............................CTGCGCTACGCTCCTGACGGT........................................................................................................................ 2112.002.00-----------------------------------------1.00---------1.00--------------------
............................GCCCTGCGCTACGCTCCTGACGGTG....................................................................................................................... 2512.002.00------------------------------------------------2.00-----------------------
.........................................................................................................TCCAGGGTCCCGCGCAGGC................................................ 1911.001.00--------1.00---------------------------------------------------------------
.....................................TACGCTCCTGACGGTGAG..................................................................................................................... 1811.001.00--------------------------------------1.00---------------------------------
..................................CGCTACGCTCCTGACGGT........................................................................................................................ 1811.001.00-------------------------------------------1.00----------------------------
....................................................................................................................GCGCAGGCATCATCGGAC...................................... 181.000.00-------------------------------1.00----------------------------------------
...........................TGCCCTGCGCTACGCTCCTGAC........................................................................................................................... 2211.001.00-------------------------------------------------1.00----------------------
........................GAATGCCCTGCGCTACG................................................................................................................................... 171.000.00----1.00-------------------------------------------------------------------
.................................GCGCTACGCTCCTGACGGT........................................................................................................................ 1911.001.00---------------------------------------------------------------1.00--------
.............................CCCTGCGCTACGCTCCTGACGG......................................................................................................................... 2211.001.00-------------------------------------------------------------------1.00----
............................................................................................................................ATCATCGGACTTCAGA................................ 161.000.00-------------------------1.00----------------------------------------------
...................................................................................TAGGCCAGTCCAGTCTCTAAGC................................................................... 2211.001.00------------------------------------1.00-----------------------------------
................................................................................................................TCCCGCGCAGGCAT.............................................. 1411.001.00--------------------------------------1.00---------------------------------
.....................TGGGAATGCCCTGCGCTACGCTCCTG............................................................................................................................. 2611.001.00--------------------------------------------------------------1.00---------
.........................................................CTGGGCTGTGGGGTCGCGG................................................................................................ 191.000.00---------------------------------------------------------------------1.00--
.......................................CGCTCCTGACGGTGAGTGCTGGGC............................................................................................................. 2411.001.00------------------------------------1.00-----------------------------------
............................GCCCTGCGCTACGCTCCTGACGGT........................................................................................................................ 2411.001.00------------------------------------1.00-----------------------------------
..................CTCTGGGAATGCCCTGCGCTA..................................................................................................................................... 2111.001.00-----------------------------------------1.00------------------------------