ID: uc001kuo.1
GENE: NOLC1(1)
chr10:103916782-103916995+


(3)
AGO1.ip 		(1)
AGO1.ip OTHER.mut 		(4)
AGO2.ip 		(1)
AGO3.ip 		(16)
B-CELL 		(12)
BRAIN 		(14)
BREAST 		(55)
CELL-LINE 		(6)
CERVIX 		(2)
FIBROBLAST 		(8)
HEART 		(5)
HELA 		(1)
KIDNEY 		(8)
LIVER 		(2)
OTHER 		(1)
RRP40.ip 		(45)
SKIN 		(1)
TESTES 		(4)
UTERUS 		(1)
XRN.ip

Sense strand
CAGGATGCCAATGCCTCTTCCCTCTTAGACATCTATAGCTTCTGGCTCAAGTAAGCCTTTCCTGTTCCATTTTGGCTATTTTCTCCCCCAAGATAGGCTGGGCTGTGTTTCTTGGTTTGGGAAGATTCCAGTCCCCTAGAAATTGGTCCAATCTACCTCAGCAGGTCTGCCAAGGTCCCAGAGCGAAAGTTACAGGCAAATGGACCAGTGGCTA
..........................................................................................((.(((..(((((((.((((((.((.((((((...))))))...)).)))))))))))))..))).))........................................................
....................................................................................85.............................................................................164................................................
SizePerfect hitTotal NormPerfect NormSRR387910(GSM843862)
antibody for ip: Ago2. (ago2 cell line)		SRR189782SRR387909(GSM843861)
specific-host: Homo sapienshost cell line: Su. (cell line)		SRR033722(GSM497067)
KMS12 cell line (KMS12). (B cell)		SRR326280(GSM769510)
total cell content of unperturbed cells was s. (cell line)		GSM450600(GSM450600)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR039193(GSM494812)
HL60 cell line is derived from acute promyelo. (cell line)		SRR033711(GSM497056)
GCB DLBCL (GCB110). (B cell)		SRR189786DRR000557(DRX000315)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR037942(GSM510480)
293DroshaTN_cand5. (cell line)		SRR094129(GSM651905)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR207116(GSM721078)
Nuclear RNA. (cell line)		SRR207115(GSM721077)
XRN1&2 knockdown. (XRN1/XRN2 cell line)		SRR326279(GSM769509)
cytoplasmic fraction was isolated using PARIS. (cell line)		RoviraIPAgo2(Rovira)
total RNA. (ago2 breast)		SRR038858(GSM458541)
MEL202. (cell line)		SRR033712(GSM497057)
Burkitt Lymphoma (BL510). (B cell)		SRR037938(GSM510476)
293Red. (cell line)		SRR553572(SRX182778)
source: Frontal Cortex. (Frontal Cortex)		SRR037940(GSM510478)
293cand5_rep2. (cell line)		SRR039192(GSM494811)
K562 cell line is derived from a CML patient . (cell line)		SRR060168(GSM565978)
5-8F_nucleus. (cell line)		SRR033718(GSM497063)
Multiple Myeloma (U266). (B cell)		SRR038863(GSM458546)
MM603. (cell line)		SRR207113(GSM721075)
IP against AGO 1 & 2. (ago1/2 cell line)		GSM450602(GSM450602)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR094132(GSM651908)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		GSM1105748AGO1(GSM1105748)
small RNA sequencing data. (ago1 hela)		SRR060983(GSM569187)
Human pre-germinal center B cell [09-001]. (cell line)		SRR390723(GSM850202)
total small RNA. (cell line)		GSM450608(GSM450608)
miRNA sequencing raw reads from post-mortem s. (brain)		DRR001489(DRX001043)
"Hela short nuclear cell fraction, control". (hela)		SRR033721(GSM497066)
Ly3 cell line (Ly3). (B cell)		SRR330893(SRX091731)
tissue: skin psoriatic uninvolveddisease stat. (skin)		GSM1105750AGO3(GSM1105750)
small RNA sequencing data. (ago3 hela)		TAX577739(Rovira)
total RNA. (breast)		SRR207112(GSM721074)
RRP40 knockdown. (RRP40 cell line)		SRR060169(GSM565979)
5-8F_cytoplasm. (cell line)		SRR189784SRR326282(GSM769512)
"Dicer mRNA was knocked down using siDicer, t. (cell line)		GSM450606(GSM450606)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR207114(GSM721076)
"IP against AGO 1 & 2, RRP40 knockdown". (ago1/2 RRP40 cell line)		SRR038861(GSM458544)
MM466. (cell line)		SRR039191(GSM494810)
PBMCs were isolated by ficoll gradient from t. (blood)		GSM450609(GSM450609)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR033724(GSM497069)
L428 cell line (L428). (B cell)		SRR033723(GSM497068)
L1236 cell line (L1236). (B cell)		SRR037941(GSM510479)
293DroshaTN. (cell line)		SRR039625(GSM531988)
HBV(-) HCV(-) HCC Tissue Sample. (liver)		SRR033716(GSM497061)
Mentle Cell Lymphoma (MCL114). (B cell)		SRR326281(GSM769511)
"Dicer mRNA was knocked down using siDicer, c. (cell line)		SRR553574(SRX182780)
source: Heart. (Heart)		SRR330906(SRX091744)
tissue: normal skindisease state: normal. (skin)		SRR039624(GSM531987)
HBV(-) HCV(-) Adjacent Tissue Sample. (liver)		SRR189787GSM450601(GSM450601)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR343332(GSM796035)
"KSHV (HHV8), EBV (HHV-4)". (cell line)		SRR029128(GSM416757)
H520. (cell line)		SRR033715(GSM497060)
Mantle Cell Lymphoma (Mino122). (B cell)		SRR342900(SRX096796)
small RNA seq of Right atrial tissue. (heart)		SRR342899(SRX096795)
small RNA seq of Left atrial tissue. (heart)		SRR330903(SRX091741)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR343333(GSM796036)
KSHV (HHV8). (cell line)		SRR330877(SRX091715)
tissue: skin psoriatic involveddisease state:. (skin)		DRR000556(DRX000314)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR029054(GSM402329)
MCF7_smallRNAseq. (cell line)		SRR094131(GSM651907)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR330866(SRX091704)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330914(SRX091752)
tissue: normal skindisease state: normal. (skin)		SRR330888(SRX091726)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330913(SRX091751)
tissue: normal skindisease state: normal. (skin)		SRR039637(GSM518474)
THP1_total_sRNAs. (cell line)		SRR330868(SRX091706)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330875(SRX091713)
tissue: skin psoriatic involveddisease state:. (skin)		SRR033727(GSM497072)
HIV-positive DL (HIV412). (B cell)		SRR039613(GSM531976)
Human Normal Liver Tissue Sample 3. (liver)		SRR107296(GSM677703)
18-30nt fraction of small RNA. (cell line)		GSM450603(GSM450603)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR330872(SRX091710)
tissue: skin psoriatic involveddisease state:. (skin)		TAX577744(Rovira)
total RNA. (breast)		SRR037939(GSM510477)
293cand5_rep1. (cell line)		SRR039616(GSM531979)
HBV(+) Distal Tissue Sample 1. (liver)		SRR033717(GSM497062)
Mentle Cell Lymphoma (MCL112). (B cell)		SRR191585(GSM715695)
196genomic small RNA (size selected RNA from . (breast)		GSM450599(GSM450599)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR060985(GSM569189)
Human naive B cell [09-001]. (cell line)		SRR039621(GSM531984)
HBV(+) HCC Tissue Sample 2. (liver)		SRR033728(GSM497073)
MALT (MALT413). (B cell)		SRR033730(GSM497075)
Lymphoblastic (ALL411). (B cell)		SRR189780(GSM714640)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR015359(GSM380324)
Germinal Center B cell (GC136). (B cell)		SRR330908(SRX091746)
tissue: normal skindisease state: normal. (skin)		TAX577453(Rovira)
total RNA. (breast)		DRR000561(DRX000319)
Isolation of RNA following immunoprecipitatio. (ago2 cell line)		GSM450610(GSM450610)
miRNA sequencing raw reads from post-mortem s. (brain)		GSM450605(GSM450605)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR330879(SRX091717)
tissue: skin psoriatic involveddisease state:. (skin)		SRR038862(GSM458545)
MM472. (cell line)		DRR000555(DRX000313)
"THP-1 whole cell RNA, no treatment". (cell line)		DRR000558(DRX000316)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR060984(GSM569188)
Human plasma cell [09-001]. (cell line)		GSM532876(GSM532876)
G547T. (cervix)		SRR330878(SRX091716)
tissue: skin psoriatic involveddisease state:. (skin)		DRR001486(DRX001040)
"Hela long cytoplasmic cell fraction, LNA(+)". (hela)		SRR039635(GSM518472)
THP1_nuc_sRNAs. (cell line)		DRR000560(DRX000318)
Isolation of RNA following immunoprecipitatio. (ago1 cell line)		TAX577746(Rovira)
total RNA. (breast)		GSM450607(GSM450607)
miRNA sequencing raw reads from post-mortem s. (brain)		DRR000559(DRX000317)
"THP-1 whole cell RNA, no treatment". (cell line)		TAX577740(Rovira)
total RNA. (breast)		SRR037937(GSM510475)
293cand2. (cell line)		GSM450598(GSM450598)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR033713(GSM497058)
Burkitt Lymphoma (BL115). (B cell)		SRR060981(GSM569185)
Human centroblast [09-001]. (cell line)		GSM956925AGO2Paz8(GSM956925)
"cell line: HEK293 cell linepassages: 15-20ip. (ago2 cell line)		SRR553575(SRX182781)
source: Kidney. (Kidney)		SRR553576(SRX182782)
source: Testis. (testes)		SRR207111(GSM721073)
Whole cell RNA. (cell line)		SRR330907(SRX091745)
tissue: normal skindisease state: normal. (skin)		SRR189781(GSM714641)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		GSM359177(GSM359177)
hela_nucl_a. (hela)		SRR038852(GSM458535)
QF1160MB. (cell line)		TAX577589(Rovira)
total RNA. (breast)		SRR330884(SRX091722)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330916(SRX091754)
tissue: normal skindisease state: normal. (skin)		TAX577745(Rovira)
total RNA. (breast)		SRR330859(SRX091697)
tissue: skin psoriatic involveddisease state:. (skin)		SRR343335TAX577743(Rovira)
total RNA. (breast)		SRR330865(SRX091703)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330922(SRX091760)
tissue: normal skindisease state: normal. (skin)		SRR330883(SRX091721)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330861(SRX091699)
tissue: skin psoriatic involveddisease state:. (skin)		SRR342898(SRX096794)
small RNA seq of Right atrial tissue. (heart)		SRR037944(GSM510482)
293DcrTN_cand5. (cell line)		SRR342894(SRX096790)
small RNA seq of Right atrial tissue. (heart)		SRR330894(SRX091732)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330889(SRX091727)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330887(SRX091725)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR029132(GSM416761)
MB-MDA231. (cell line)		TAX577741(Rovira)
total RNA. (breast)		SRR330880(SRX091718)
tissue: skin psoriatic involveddisease state:. (skin)		SRR363673(GSM830250)
cell type: human foreskin fibroblasts (HFF)tr. (fibroblast)		SRR330891(SRX091729)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330899(SRX091737)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330919(SRX091757)
tissue: normal skindisease state: normal. (skin)		SRR039620(GSM531983)
HBV(+) Adjacent Tissue Sample 2. (liver)		SRR330874(SRX091712)
tissue: skin psoriatic involveddisease state:. (skin)		SRR094130(GSM651906)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR189779(GSM714639)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR033726(GSM497071)
Mututated CLL (CLLM633). (B cell)		SRR040028(GSM532913)
G026N. (cervix)		SRR330867(SRX091705)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330860(SRX091698)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330902(SRX091740)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR444058(SRX128906)
Sample 16cDNABarcode: AF-PP-335: ACG CTC TTC . (skin)		SRR039636(GSM518473)
THP1_cyto_sRNAs. (cell line)		SRR029129(GSM416758)
SW480. (cell line)		SRR330921(SRX091759)
tissue: normal skindisease state: normal. (skin)		SRR330915(SRX091753)
tissue: normal skindisease state: normal. (skin)		SRR330917(SRX091755)
tissue: normal skindisease state: normal. (skin)		SRR040018(GSM532903)
G701N. (cervix)		SRR330896(SRX091734)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330905(SRX091743)
tissue: normal skindisease state: normal. (skin)		SRR191471(GSM715581)
119genomic small RNA (size selected RNA from . (breast)		TAX577580(Rovira)
total RNA. (breast)		SRR342895(SRX096791)
small RNA seq of Left atrial tissue. (heart)		SRR330885(SRX091723)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR342897(SRX096793)
small RNA seq of Left atrial tissue. (heart)		SRR330900(SRX091738)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR107297(GSM677704)
18-30nt fraction of small RNA. (cell line)		SRR040010(GSM532895)
G529N. (cervix)		SRR444049(SRX128897)
Sample 9cDNABarcode: AF-PP-334: ACG CTC TTC C. (skin)		SRR191601(GSM715711)
58genomic small RNA (size selected RNA from t. (breast)		SRR363674(GSM830251)
cell type: human foreskin fibroblasts (HFF)tr. (fibroblast)		SRR342896(SRX096792)
small RNA seq of Right atrial tissue. (heart)		SRR330923(SRX091761)
tissue: normal skindisease state: normal. (skin)		SRR330886(SRX091724)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR039623(GSM531986)
HCV(+) HCC Tissue Sample. (liver)		SRR444060(SRX128908)
Sample 18cDNABarcode: AF-PP-340: ACG CTC TTC . (skin)		SRR039611(GSM531974)
Human Normal Liver Tissue Sample 1. (liver)		SRR040031(GSM532916)
G013T. (cervix)		SRR040015(GSM532900)
G623T. (cervix)
.........................................................................................AAGATAGGCTGGGCTGTGTTTCT......................................................................................................23178.0078.0013.00--3.001.004.002.003.001.003.001.00-3.001.001.00-4.00-4.002.00-2.00--1.00-1.00--1.002.001.00--1.001.001.00----1.00--2.001.00------1.00---1.001.001.001.00-1.00------------1.00--1.00-------1.00--1.00-----1.00-1.001.001.00----1.00----1.00-1.00-------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTC.......................................................................................................22155.0055.0012.00-8.002.002.00-2.001.00---2.002.00------1.00-1.001.00---1.001.00--1.00-1.00-------------2.00-2.00-1.00-1.002.001.00---------1.00------1.00----1.00--1.00--------------------------------1.00-1.00----1.00--1.00-------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTT........................................................................................................21145.0045.004.00--5.00--1.001.00-1.00-3.00--1.00--2.00----1.00----1.00-1.00--1.001.00----1.00--1.002.002.00-----2.001.001.00----1.001.00---------1.00--1.00-1.00-----1.00--------1.00-----1.00-1.00---1.00-----1.00-1.00----------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTT.........................................................................................................20116.0016.00--5.00-1.001.00---------1.00--------2.00-1.001.00-1.00------1.00----------------------------1.00----------------------------------------------------1.00-----------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCTCAG.....................................................22111.0011.00-8.00-------------------------------------2.00------------------------------------------------------------------1.00-----------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTCTTGG...................................................................................................2316.006.00----------4.00----1.00------------------------------------------------------------------------------------1.00-----------------------------------------------------------------------------------
.......................CTTAGACATCTATAGCTTCTGGC........................................................................................................................................................................2315.005.00--------------------4.00------------------------------------------------------------1.00------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTCTT.....................................................................................................2414.004.004.00---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTAA......................................................................................................2314.0045.00----------------------------1.00---------------------------------------1.00------1.00---------------1.00--------------------------------------------------------------------------------------------
........................................................................................CAAGATAGGCTGGGCTGTGTTT........................................................................................................2214.004.00---1.00---------2.00--------------------------1.00-----------------------------------------------------------------------------------------------------------------------------------------------
..........................................................................................AGATAGGCTGGGCTGTGTTTCT......................................................................................................2213.003.002.00------------------------------1.00--------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTT.......................................................................................................2213.0045.00------------------------------------------------------1.00-------1.00---1.00---------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGT..........................................................................................................1913.003.00-------------------------------------2.00--1.00-----------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTA........................................................................................................2113.0016.00----1.00-1.00-------------------------------------------------------------------------------1.00-------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTA.......................................................................................................2213.0045.00---------1.00-------------1.00-----------------------1.00----------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTCTTG....................................................................................................2212.002.00-1.00-------------------------------------------------1.00------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTTT......................................................................................................2312.0045.00-1.00--------------------------------------------------------1.00-----------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTTATG....................................................................................................2512.0045.00-------------------------2.00--------------------------------------------------------------------------------------------------------------------------------------------------------------
........................................................................................CAAGATAGGCTGGGCTGTGTTTC.......................................................................................................2312.002.00---1.00--------------------------------------------------------1.00---------------------------------------------------------------------------------------------------------------------------
............................................................................................................................................................................AGGTCCCAGAGCGAAAGTT.......................1912.002.00-----------------------------------------------1.00------------------------------------------------------1.00---------------------------------------------------------------------------------
..........................................................................................AGATAGGCTGGGCTGTGTTT........................................................................................................2012.002.00-----------------------2.00----------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTAA.......................................................................................................2212.0016.00-------1.00--------------------------------------------------------------------------1.00-----------------------------------------------------------------------------------------------------
..........ATGCCTCTTCCCTCTTAGACATCTACAGC...............................................................................................................................................................................291.000.00------------------------------------------------------------------------------------------1.00---------------------------------------------------------------------------------------------
.....................................................................................................................................................................TCTGCCAAGGTCCCAGAGCGA............................2111.001.00--------------------------------------------------------------------------------1.00-------------------------------------------------------------------------------------------------------
...........................................................................................GATAGGCTGGGCTGTGTTTCT......................................................................................................2111.001.00----------------------------1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------
..........................AGACATCTATAGCTTCTG..........................................................................................................................................................................1811.001.00---------------------1.00------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................................................................................................CCAAGGTCCCAGAGCGAAAGTTACAG...................2611.001.00--------------------------------------1.00-------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCTCAA.....................................................2211.001.00-1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................................................................AGTTACAGGCAAATGGACCAGTGGC..2511.001.00---------------------------------------------------------------------------------------------------------------------1.00------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGT............................................................................................................1711.001.00----1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCTCA......................................................2111.001.00---------------1.00------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCTAAG.....................................................221.000.00------------------------------------------------------------------------------------1.00---------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTCCTGG...................................................................................................2311.001.00--------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTAA........................................................................................................2111.003.00-----------------------------------------------------------------------------------------------------1.00----------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTAT......................................................................................................2311.0045.00----1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................GATAGGCTGGGCTGTGTTTCTTG....................................................................................................2311.001.00----------------------------1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTCTTGGA..................................................................................................2411.006.00--------------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTAATG....................................................................................................2511.0045.00-------------------------1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------
.................................................................................................................................................................................CCAGAGCGAAAGTTACAGGCA................2111.001.00-------------------------------------------------------------------------------------------------------------------1.00--------------------------------------------------------------------
........................TTAGACATCTATAGCTTCTGGCTCAA....................................................................................................................................................................2611.001.00-------------------------------------------------------------------------------------------------------------------------1.00--------------------------------------------------------------
.......................................................................................CCAAGATAGGCTGGGCTGTGTTTC.......................................................................................................2411.001.00-------------------1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................GATAGGCTGGGCTGTGTTTCTT.....................................................................................................2211.001.00--------------------------------------------------------------------------------------------------------------------1.00-------------------------------------------------------------------
......................................................................................................................................................................CTGCCAAGGTCCCAGAGCGAAAGTTACAGGCAAATG............3611.001.00---------------1.00------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGGTT........................................................................................................211.000.00-----------------1.00----------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCTCAGA....................................................2311.0011.00---------------------------------------------------------------------1.00------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTCTAA....................................................................................................2511.0078.00--------------------------------------------------------------------------------------------1.00-------------------------------------------------------------------------------------------
..............................................................................................................................................................................................TACAGGCAAATGGACCAGTGGCT.2311.001.00-----------------1.00----------------------------------------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTT........................................................................................................1811.001.00-----------------------------------------------------------------------------------1.00----------------------------------------------------------------------------------------------------
............................ACATCTATAGCTTCTGGCTCAACAG.................................................................................................................................................................251.000.00-1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
..........................................................................................AGATAGGCTGGGCTGTGTTTC.......................................................................................................2111.001.00---------------------------------------------1.00------------------------------------------------------------------------------------------------------------------------------------------
..................................................................................................................................................................................CAGAGCGAAAGTTACAGGC.................1911.001.00----------------------------------1.00-----------------------------------------------------------------------------------------------------------------------------------------------------
....................................................................................................................................................................................................CAAATGGACCAGTGGCTA1811.001.00----------------------1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------------
........................................................................................CAAGATAGGCTGGGCTGTGTCTC.......................................................................................................231.000.00--------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
........................................................................................................................................TAGAAATTGGTCCAATCTACCT........................................................2211.001.00--------------------------------------------------------------------------------------------------------1.00-------------------------------------------------------------------------------
..........................AGACATCTATAGCTTCTGGCTCAAGTAA................................................................................................................................................................2811.001.00-----------------------------------------------------------------------------------------1.00----------------------------------------------------------------------------------------------
...................................................................................................................................................................................................GCAAATGGACCAGTGGCT.1811.001.00---------------------------------1.00------------------------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTCTTGGT..................................................................................................2411.001.00-----------------------------------1.00----------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................................................................................................................AAAGTTACAGGCAAATGGACCAGTGGCTA2911.001.00-1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................AAATTGGTCCAATCTACCACAC.....................................................221.000.00-1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTAG......................................................................................................2011.001.00----1.00-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGGGTT.........................................................................................................201.000.00--------------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
..........................................................................................AGATAGGCTGGGCTGTGTTTA.......................................................................................................2111.002.00-----1.00----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGGGT..........................................................................................................191.000.00-----------------------------------------------------------------------------------------------------------------1.00----------------------------------------------------------------------
.........................................................................................AAGATAGGCTGGGCTGTGTTTCC......................................................................................................2311.0055.00--------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
................................CTATAGCTTCTGGCTCAAGTCTGC..............................................................................................................................................................241.000.00-------------1.00--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
............................................................................................ATAGGCTGGGCTGTGTTTC.......................................................................................................1911.001.00-------------------------------------------------------------------------------------------------------------1.00--------------------------------------------------------------------------
.........................................................................................................................................................................................AAAGTTACAGGCAAATGGACC........2120.500.50-0.50--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
...........................................................................................................................................................................................AGTTACAGGCAAATGGACC........1920.500.50----------------------------------------------------------------------------------------------------------------------------0.50-----------------------------------------------------------
.....................................................................................................................................................................................AGCGAAAGTTACAGGCAAATGGACCA.......2620.500.50----------------------0.50-----------------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................................................................................................................AAAGTTACAGGCAAATGGACCA.......2220.500.50---------------------------------0.50------------------------------------------------------------------------------------------------------------------------------------------------------
..................................................................................................................................................................................................GGCAAATGGACCAGTGGC..1820.500.50-----------------------------------------------------------0.50----------------------------------------------------------------------------------------------------------------------------
.........................................................................................................................................................................................AAAGTTACAGGCAAATGGACCAGTG....2520.500.50-------------0.50--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
....................................................................................................................................................CAATCTACCTCAGCAG..................................................1620.500.50--------------------------------0.50-------------------------------------------------------------------------------------------------------------------------------------------------------
.........................................................................................................................................................................................AAAGTTACAGGCAAATGGACCAG......2320.500.50-0.50--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
.................................................................................................................................................................................CCAGAGCGAAAGT........................13100.100.10-----------------------------------------------------------------------------------------------------------------------------------------0.10----------------------------------------------

Antisense strand
CAGGATGCCAATGCCTCTTCCCTCTTAGACATCTATAGCTTCTGGCTCAAGTAAGCCTTTCCTGTTCCATTTTGGCTATTTTCTCCCCCAAGATAGGCTGGGCTGTGTTTCTTGGTTTGGGAAGATTCCAGTCCCCTAGAAATTGGTCCAATCTACCTCAGCAGGTCTGCCAAGGTCCCAGAGCGAAAGTTACAGGCAAATGGACCAGTGGCTA
..........................................................................................((.(((..(((((((.((((((.((.((((((...))))))...)).)))))))))))))..))).))........................................................
....................................................................................85.............................................................................164................................................
SizePerfect hitTotal NormPerfect NormSRR387910(GSM843862)
antibody for ip: Ago2. (ago2 cell line)		SRR189782SRR387909(GSM843861)
specific-host: Homo sapienshost cell line: Su. (cell line)		SRR033722(GSM497067)
KMS12 cell line (KMS12). (B cell)		SRR326280(GSM769510)
total cell content of unperturbed cells was s. (cell line)		GSM450600(GSM450600)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR039193(GSM494812)
HL60 cell line is derived from acute promyelo. (cell line)		SRR033711(GSM497056)
GCB DLBCL (GCB110). (B cell)		SRR189786DRR000557(DRX000315)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR037942(GSM510480)
293DroshaTN_cand5. (cell line)		SRR094129(GSM651905)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR207116(GSM721078)
Nuclear RNA. (cell line)		SRR207115(GSM721077)
XRN1&2 knockdown. (XRN1/XRN2 cell line)		SRR326279(GSM769509)
cytoplasmic fraction was isolated using PARIS. (cell line)		RoviraIPAgo2(Rovira)
total RNA. (ago2 breast)		SRR038858(GSM458541)
MEL202. (cell line)		SRR033712(GSM497057)
Burkitt Lymphoma (BL510). (B cell)		SRR037938(GSM510476)
293Red. (cell line)		SRR553572(SRX182778)
source: Frontal Cortex. (Frontal Cortex)		SRR037940(GSM510478)
293cand5_rep2. (cell line)		SRR039192(GSM494811)
K562 cell line is derived from a CML patient . (cell line)		SRR060168(GSM565978)
5-8F_nucleus. (cell line)		SRR033718(GSM497063)
Multiple Myeloma (U266). (B cell)		SRR038863(GSM458546)
MM603. (cell line)		SRR207113(GSM721075)
IP against AGO 1 & 2. (ago1/2 cell line)		GSM450602(GSM450602)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR094132(GSM651908)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		GSM1105748AGO1(GSM1105748)
small RNA sequencing data. (ago1 hela)		SRR060983(GSM569187)
Human pre-germinal center B cell [09-001]. (cell line)		SRR390723(GSM850202)
total small RNA. (cell line)		GSM450608(GSM450608)
miRNA sequencing raw reads from post-mortem s. (brain)		DRR001489(DRX001043)
"Hela short nuclear cell fraction, control". (hela)		SRR033721(GSM497066)
Ly3 cell line (Ly3). (B cell)		SRR330893(SRX091731)
tissue: skin psoriatic uninvolveddisease stat. (skin)		GSM1105750AGO3(GSM1105750)
small RNA sequencing data. (ago3 hela)		TAX577739(Rovira)
total RNA. (breast)		SRR207112(GSM721074)
RRP40 knockdown. (RRP40 cell line)		SRR060169(GSM565979)
5-8F_cytoplasm. (cell line)		SRR189784SRR326282(GSM769512)
"Dicer mRNA was knocked down using siDicer, t. (cell line)		GSM450606(GSM450606)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR207114(GSM721076)
"IP against AGO 1 & 2, RRP40 knockdown". (ago1/2 RRP40 cell line)		SRR038861(GSM458544)
MM466. (cell line)		SRR039191(GSM494810)
PBMCs were isolated by ficoll gradient from t. (blood)		GSM450609(GSM450609)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR033724(GSM497069)
L428 cell line (L428). (B cell)		SRR033723(GSM497068)
L1236 cell line (L1236). (B cell)		SRR037941(GSM510479)
293DroshaTN. (cell line)		SRR039625(GSM531988)
HBV(-) HCV(-) HCC Tissue Sample. (liver)		SRR033716(GSM497061)
Mentle Cell Lymphoma (MCL114). (B cell)		SRR326281(GSM769511)
"Dicer mRNA was knocked down using siDicer, c. (cell line)		SRR553574(SRX182780)
source: Heart. (Heart)		SRR330906(SRX091744)
tissue: normal skindisease state: normal. (skin)		SRR039624(GSM531987)
HBV(-) HCV(-) Adjacent Tissue Sample. (liver)		SRR189787GSM450601(GSM450601)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR343332(GSM796035)
"KSHV (HHV8), EBV (HHV-4)". (cell line)		SRR029128(GSM416757)
H520. (cell line)		SRR033715(GSM497060)
Mantle Cell Lymphoma (Mino122). (B cell)		SRR342900(SRX096796)
small RNA seq of Right atrial tissue. (heart)		SRR342899(SRX096795)
small RNA seq of Left atrial tissue. (heart)		SRR330903(SRX091741)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR343333(GSM796036)
KSHV (HHV8). (cell line)		SRR330877(SRX091715)
tissue: skin psoriatic involveddisease state:. (skin)		DRR000556(DRX000314)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR029054(GSM402329)
MCF7_smallRNAseq. (cell line)		SRR094131(GSM651907)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR330866(SRX091704)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330914(SRX091752)
tissue: normal skindisease state: normal. (skin)		SRR330888(SRX091726)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330913(SRX091751)
tissue: normal skindisease state: normal. (skin)		SRR039637(GSM518474)
THP1_total_sRNAs. (cell line)		SRR330868(SRX091706)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330875(SRX091713)
tissue: skin psoriatic involveddisease state:. (skin)		SRR033727(GSM497072)
HIV-positive DL (HIV412). (B cell)		SRR039613(GSM531976)
Human Normal Liver Tissue Sample 3. (liver)		SRR107296(GSM677703)
18-30nt fraction of small RNA. (cell line)		GSM450603(GSM450603)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR330872(SRX091710)
tissue: skin psoriatic involveddisease state:. (skin)		TAX577744(Rovira)
total RNA. (breast)		SRR037939(GSM510477)
293cand5_rep1. (cell line)		SRR039616(GSM531979)
HBV(+) Distal Tissue Sample 1. (liver)		SRR033717(GSM497062)
Mentle Cell Lymphoma (MCL112). (B cell)		SRR191585(GSM715695)
196genomic small RNA (size selected RNA from . (breast)		GSM450599(GSM450599)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR060985(GSM569189)
Human naive B cell [09-001]. (cell line)		SRR039621(GSM531984)
HBV(+) HCC Tissue Sample 2. (liver)		SRR033728(GSM497073)
MALT (MALT413). (B cell)		SRR033730(GSM497075)
Lymphoblastic (ALL411). (B cell)		SRR189780(GSM714640)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR015359(GSM380324)
Germinal Center B cell (GC136). (B cell)		SRR330908(SRX091746)
tissue: normal skindisease state: normal. (skin)		TAX577453(Rovira)
total RNA. (breast)		DRR000561(DRX000319)
Isolation of RNA following immunoprecipitatio. (ago2 cell line)		GSM450610(GSM450610)
miRNA sequencing raw reads from post-mortem s. (brain)		GSM450605(GSM450605)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR330879(SRX091717)
tissue: skin psoriatic involveddisease state:. (skin)		SRR038862(GSM458545)
MM472. (cell line)		DRR000555(DRX000313)
"THP-1 whole cell RNA, no treatment". (cell line)		DRR000558(DRX000316)
"THP-1 whole cell RNA, after 3 day treatment . (cell line)		SRR060984(GSM569188)
Human plasma cell [09-001]. (cell line)		GSM532876(GSM532876)
G547T. (cervix)		SRR330878(SRX091716)
tissue: skin psoriatic involveddisease state:. (skin)		DRR001486(DRX001040)
"Hela long cytoplasmic cell fraction, LNA(+)". (hela)		SRR039635(GSM518472)
THP1_nuc_sRNAs. (cell line)		DRR000560(DRX000318)
Isolation of RNA following immunoprecipitatio. (ago1 cell line)		TAX577746(Rovira)
total RNA. (breast)		GSM450607(GSM450607)
miRNA sequencing raw reads from post-mortem s. (brain)		DRR000559(DRX000317)
"THP-1 whole cell RNA, no treatment". (cell line)		TAX577740(Rovira)
total RNA. (breast)		SRR037937(GSM510475)
293cand2. (cell line)		GSM450598(GSM450598)
miRNA sequencing raw reads from post-mortem s. (brain)		SRR033713(GSM497058)
Burkitt Lymphoma (BL115). (B cell)		SRR060981(GSM569185)
Human centroblast [09-001]. (cell line)		GSM956925AGO2Paz8(GSM956925)
"cell line: HEK293 cell linepassages: 15-20ip. (ago2 cell line)		SRR553575(SRX182781)
source: Kidney. (Kidney)		SRR553576(SRX182782)
source: Testis. (testes)		SRR207111(GSM721073)
Whole cell RNA. (cell line)		SRR330907(SRX091745)
tissue: normal skindisease state: normal. (skin)		SRR189781(GSM714641)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		GSM359177(GSM359177)
hela_nucl_a. (hela)		SRR038852(GSM458535)
QF1160MB. (cell line)		TAX577589(Rovira)
total RNA. (breast)		SRR330884(SRX091722)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330916(SRX091754)
tissue: normal skindisease state: normal. (skin)		TAX577745(Rovira)
total RNA. (breast)		SRR330859(SRX091697)
tissue: skin psoriatic involveddisease state:. (skin)		SRR343335TAX577743(Rovira)
total RNA. (breast)		SRR330865(SRX091703)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330922(SRX091760)
tissue: normal skindisease state: normal. (skin)		SRR330883(SRX091721)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330861(SRX091699)
tissue: skin psoriatic involveddisease state:. (skin)		SRR342898(SRX096794)
small RNA seq of Right atrial tissue. (heart)		SRR037944(GSM510482)
293DcrTN_cand5. (cell line)		SRR342894(SRX096790)
small RNA seq of Right atrial tissue. (heart)		SRR330894(SRX091732)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330889(SRX091727)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330887(SRX091725)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR029132(GSM416761)
MB-MDA231. (cell line)		TAX577741(Rovira)
total RNA. (breast)		SRR330880(SRX091718)
tissue: skin psoriatic involveddisease state:. (skin)		SRR363673(GSM830250)
cell type: human foreskin fibroblasts (HFF)tr. (fibroblast)		SRR330891(SRX091729)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330899(SRX091737)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330919(SRX091757)
tissue: normal skindisease state: normal. (skin)		SRR039620(GSM531983)
HBV(+) Adjacent Tissue Sample 2. (liver)		SRR330874(SRX091712)
tissue: skin psoriatic involveddisease state:. (skin)		SRR094130(GSM651906)
small RNA(18-35nt)small RNA deep sequencing o. (uterus)		SRR189779(GSM714639)
cell line: HEK293clip variant: PAR-CLIPenzyma. (cell line)		SRR033726(GSM497071)
Mututated CLL (CLLM633). (B cell)		SRR040028(GSM532913)
G026N. (cervix)		SRR330867(SRX091705)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330860(SRX091698)
tissue: skin psoriatic involveddisease state:. (skin)		SRR330902(SRX091740)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR444058(SRX128906)
Sample 16cDNABarcode: AF-PP-335: ACG CTC TTC . (skin)		SRR039636(GSM518473)
THP1_cyto_sRNAs. (cell line)		SRR029129(GSM416758)
SW480. (cell line)		SRR330921(SRX091759)
tissue: normal skindisease state: normal. (skin)		SRR330915(SRX091753)
tissue: normal skindisease state: normal. (skin)		SRR330917(SRX091755)
tissue: normal skindisease state: normal. (skin)		SRR040018(GSM532903)
G701N. (cervix)		SRR330896(SRX091734)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR330905(SRX091743)
tissue: normal skindisease state: normal. (skin)		SRR191471(GSM715581)
119genomic small RNA (size selected RNA from . (breast)		TAX577580(Rovira)
total RNA. (breast)		SRR342895(SRX096791)
small RNA seq of Left atrial tissue. (heart)		SRR330885(SRX091723)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR342897(SRX096793)
small RNA seq of Left atrial tissue. (heart)		SRR330900(SRX091738)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR107297(GSM677704)
18-30nt fraction of small RNA. (cell line)		SRR040010(GSM532895)
G529N. (cervix)		SRR444049(SRX128897)
Sample 9cDNABarcode: AF-PP-334: ACG CTC TTC C. (skin)		SRR191601(GSM715711)
58genomic small RNA (size selected RNA from t. (breast)		SRR363674(GSM830251)
cell type: human foreskin fibroblasts (HFF)tr. (fibroblast)		SRR342896(SRX096792)
small RNA seq of Right atrial tissue. (heart)		SRR330923(SRX091761)
tissue: normal skindisease state: normal. (skin)		SRR330886(SRX091724)
tissue: skin psoriatic uninvolveddisease stat. (skin)		SRR039623(GSM531986)
HCV(+) HCC Tissue Sample. (liver)		SRR444060(SRX128908)
Sample 18cDNABarcode: AF-PP-340: ACG CTC TTC . (skin)		SRR039611(GSM531974)
Human Normal Liver Tissue Sample 1. (liver)		SRR040031(GSM532916)
G013T. (cervix)		SRR040015(GSM532900)
G623T. (cervix)
.AGGATGCCAATGCCTAAG................................................................................................................................................................................................... 1814.170.00--------------0.17--------0.330.17---------0.33--------------------------0.330.331.33--0.17---0.17-0.171.00-------------------------------------------------0.83-0.500.170.33-0.500.500.17-0.330.500.17-0.170.330.330.33--0.17-0.170.170.17-0.33-0.170.170.170.17--0.170.170.17-0.170.17--0.170.170.170.17---0.17-0.17--0.170.17-0.170.170.170.17
.AGGATGCCAATGCCT...................................................................................................................................................................................................... 1565.505.50------------------------------------------------------------0.17---0.17----0.17-0.17-0.17-----------------------------------------------------0.17---0.330.330.17--0.330.17----0.330.170.330.170.17-0.33------0.170.17---0.17--0.170.17----0.170.17--0.17-0.170.17-------
.AGGATGCCAATGCCTAAGC.................................................................................................................................................................................................. 192.000.00------------------------------------------------------------0.17------0.170.17-------------------------------------------------------0.170.170.330.17-------0.330.17----------0.17------------------------------------
.................................................................................................................................................GTCCAATCTACCTCAAGTT.................................................. 192.000.00-------------------------------------------------------2.00--------------------------------------------------------------------------------------------------------------------------------
.AGGATGCCAATGCCTAA.................................................................................................................................................................................................... 171.170.00-----------------------------------------------------------------0.17------------------------------------------------------------0.17--0.17--0.17--------0.33-----------------------------0.17------------
..............................................................TGTTCCATTTTGGCTAAT...................................................................................................................................... 181.000.00---------------------------------------------------------------------------------------------------------------1.00------------------------------------------------------------------------
....................................................................................................................................................CAATCTACCTCAGCAAAA................................................ 181.000.00-------------------------------1.00--------------------------------------------------------------------------------------------------------------------------------------------------------
....................................................................................................................................................CAATCTACCTCAGCATA................................................. 171.000.00-----1.00----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
................................................................................................................................................GGTCCAATCTACCTCAGCT................................................... 191.000.00--------1.00-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
................................................................................................................................................................GCAGGTCTGCCAAGG....................................... 1530.670.67--------------------------------------------------------------------------------------------------------------------------------0.67-------------------------------------------------------
.................................TATAGCTTCTGGCTCA..................................................................................................................................................................... 1640.250.25------------------------------------------------------------------------------------------------------------------------------------------------------0.25---------------------------------
.AGGATGCCAATGCCTAATA.................................................................................................................................................................................................. 190.170.00-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------0.17----