D. melanogaster 310-313 Cluster Investigation

Notes:

  1. The 310 - 313 cluster seems to have functional related to development. There are an enrichment of sRNAseq expression in our embryo libraries accross all species (except for grimshawi, for which we have no embryo libraries).
  2. This cluster has a burst of miRNAs in the obscura lineage. Note that in the pseudobscura lineage, most of these 'new' miRNAs have already been annotated in miRBase 17. D. persimilis annotation from miRBase cannot be viewed on the UCSC browser because the UCSC browser persimilis' chromosomes are in a different format than that of what miRBase (or even flybase) reports. That is UCSC has chromosomes with prefix "scaffold" whereas miRBase/Flybase has prefix of "super".

Similarity

similarity

Candidate Loci

The candidate loci are shown in red. Note that, many species-specific newly evolved miRNAs are already annotated in miRBase, for example, see D. pseudobscura.

droSim1

 

 

droSec1

 

 

droYak2

 

 

droEre2

 

 

droAna3

 

 

dp4

 

 

droPer1

 

 

droWil1

 

 

droVir3

 

 

droMoj3

 

 

droGri2